Distinct characteristics of VEXAS-causative UBA1 M41 and recurrent functional non-M41 mutations.

Sakuma M, Wang AK, Magaziner SJ, Keane SP, Meggendorfer M, Kern W, Haferlach C, Haferlach T, Beck DB, Walter W. Distinct characteristics of VEXAS-causative UBA1 M41 and recurrent functional non-M41 mutations. Leukemia. 2025 Dec;39(12):2872-2880. doi: 10.1038/s41375-025-02775-4. Epub 2025 Oct 9. PMID: 41068485; PMCID: PMC12634433. Online Article