Maria Sirenko
Maria is a Postdoctoral Fellow in the lab co-mentored by Dr. Iannis Aifantis. She is working on identifying novel drivers of overlapping inflammatory disease and myeloid malignancy. She received her B.S. in Biomedical Engineering from Cornell University and her Ph.D. at Memorial Sloan Kettering Cancer Center in the lab of Dr. Elli Papaemmanuil. During her Ph.D., she established integrative single cell frameworks to study genetic and cellular heterogeneity in IDH-mutated acute myeloid leukemia and defined how cooperative mutations shape treatment response. She also studied the overlap of VEXAS and myelodysplastic syndromes (MDS) and defined the prevalence, co-mutation patterns, and clinical associations of UBA1 mutations in a large, international cohort of MDS patients.
