Aplastic Anemia and MDS International Foundation Research Award!

We are excited to announce that we have been awarded an Aplastic Anemia and MDS International Foundation Research Award! Thank you for the support, we are eager to tackle some of the genetic discovery in acquired bone marrow failure syndromes.

VEXAS syndrome on CNN

We are proud to be highlighted on a piece about VEXAS syndrome and our recent JAMA study on CNN. We are hoping that this will raise awareness about the disease given its prevalence, and severity.

 

https://amp.cnn.com/cnn/2023/01/24/health/vexas-syndrome-prevalence-study-wellness/index.html

Our collaborative work published in JAMA!

Very proud to see our work as a collaboration between NYU, NIH, and Geisinger published in JAMA today. We show the prevalence, penetrance and expressivity of VEXAS syndrome and help better define the disease. Congratulations to the team!

Screen Shot 2023 01 24 at 5.56.55 PM

Screen Shot 2023 01 24 at 5.56.55 PM

Jeffrey Modell Foundation

We are excited and thankful for our work being selected for a Jeffrey Modell Foundation Translational Research Program Grant Award.

Welcome Flore!

We are excited to have our new post doctoral fellow Dr. Flore Castellan join the team! Welcome aboard!

 

 

Welcome Ayana and Niharika!

Welcome to our two new post-doctoral fellows: Niharika Srivastava and Ayana Sawai-Frantz! We are excited to have you on the team!

 

 

Welcome Bibi!

Welcome Bibi! Bibi Subhan is rotating in our lab this fall!

Our lab’s first paper!

We are excited to share that our lab’s first paper Translation of cytoplasmic UBA1 contributes to VEXAS syndrome pathogenesis” is now published at Blood.

Our work highlights a genotype-phenotype correlation in VEXAS syndrome based on levels of UBA1b translation. This was a tremendous collaboration with Drs. Achim Werner and Peter Grayson and a big congratulation to the rest of the team!

Welcome Athena and Mary!

We are excited to welcome a new summer student, Athena Lam , and a research associate, Mary Likhite. We are excited to have both of you on the team!

New review from the lab- Disorders of ubiquitylation: unchained inflammation

We are proud to announce a new review from our lab and colleagues at the NIH in Nature Reviews Rheumatology. Here we outline immune dysregulation disorders caused by mutations in ubiquitylation enzymes and highlight how these shared mechanisms may lead to new treatments. Enjoy!