Entries by David Beck

New Publication!

We are excited to share that our collaborative work with the Werner lab at NIH was published in the EMBO Journal  (https://www.embopress.org/doi/full/10.1038/s44318-024-00046-z). In this work, we characterize disease causing mutation in UBA1  in vitro and in vivo to define the mechanisms underlying VEXAS syndrome, XL-SMA, and Lung Cancer in Never Smokers (LCINS). We define an […]

Edward P. Evans MDS Foundation

We are excited to announce that we have received funding from the Edward P. Evans Foundation to study our mouse models of UBA1, clonal hematopoiesis, and bone marrow failure. Thank you for this EvansMDS Discovery Research Grant 2023, we are excited to start tackling this question!

New publication from the lab!

We are proud that our collaboration with Dr. Neal Young’s group studying inflammatory signals in VEXAS syndrome has been published! Please check out the link below: https://pubmed.ncbi.nlm.nih.gov/37586319/.

Welcome Mei-Kay and Brecca!

We are excited to welcome both Mei-Kay Wong, a new genetic counselor for the laboratory and Brecca Miller, a shared PhD study with Dr. Kelly Ruggles! Welcome aboard the team.

UBA1 and Clonal Hematopoiesis- New Publication

We are proud of our recently published paper “Spectrum of clonal hematopoiesis in VEXAS syndrome” outlining the co-occurrence and clinical importance of CH mutations in VEXAS syndrome. This was an exciting collaboration with colleagues from the NIH and Mayo Clinic, and very appreciative of the team work.